Scientific controversy with radioisotopic dating

Hematological and iron-related analytes: reference data for persons aged 1 year and over: United States, 1988-94. Moreover, data derived from white subjects are not provided.

In these and many other previous analyses of hematologic data the subjects have been divided into age in deciles. Because there are virtually no differences in hemoglobin values of men in the age range of 20 to 59 or in women aged 20 through 49 in our data or in the analysis of the NHANES-III hemoglobin values,12 we have used these age ranges representing younger adults, and the ages beyond these ranges to represent older adults.

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White Americans are a genetic mixture of persons from various parts of Europe and the Middle East.

Data regarding ancestral origin are available in the Scripps Kaiser database but not in NHANES-III, so that direct comparison is not possible.

It is likely that more of the black population of San Diego originates from the Northeast and the Midwest; therefore, San Diego may have greater white admixture than the NHANES sample.

However, this has not been documented by the study of genetic markers in either data set.

This serves to eliminate most subjects with iron deficiency anemia and also many of those with the anemia of chronic inflammation, in which the transferrin saturation is also usually low.

We were also able to determine whether excessive alcohol intake, diabetes mellitus, renal failure, or inflammatory markers (C-reactive protein in NHANES, erythrocyte sedimentation rate in Scripps-Kaiser, elevated serum ferritin, or leukocytosis) affected the hemoglobin concentrations in these populations.

Hematological and iron-related analytes: reference data for persons aged 1 year and over: United States, 1988-94. This would obviously be true with the population designated "black," because it is well known that the genes of individuals classified as African American could be anywhere between 10% and 90% of European origin, with most of the remaining genome being of African origin.

As pointed out earlier, differences in the degree of the European admixture could well account for the small differences in hemoglobin concentrations documented in the 2 data sets.

In any analysis, elimination of subjects from consideration is constrained by the data that are available.

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