national dating web site - Sedating dose

[ Read the disclaimer | For Adult Intensive Care Unit Sedation: Generally initiate at one mcg/kg over 10 minutes, followed by a maintenance infusion of 0.2 to 0.7 mcg/kg/hour.

For Adult Procedural Sedation: Generally initiate at one mcg/kg over 10 minutes, followed by a maintenance infusion initiated at 0.6 mcg/kg/hour and titrated to achieve desired clinical effect with doses ranging from 0.2 to 1 mcg/kg/hour.

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Alternative Doses: Recommended for patients over 65 years of age and awake fiberoptic intubation patients.

Dosage Adjustment Due to possible pharmacodynamic interactions, a reduction in dosage of Precedex or other concomitant anesthetics, sedatives, hypnotics or opioids may be required when co-administered Dosage reductions may need to be considered for adult patients with hepatic impairment, and geriatric patients [see package insert] WARNINGS AND PRECAUTIONS: DOSAGE FORMS AND STRENGTHS: 1] Precedex Injection, 200 mcg/2 m L (100 mcg/m L) in a glass vial. 2] Precedex in 0.9% Sodium Chloride Injection 200 mcg/50 m L (4 mcg/m L) in a 50 m L glass bottle. 3] Precedex in 0.9% Sodium Chloride Injection 400 mcg/100 m L (4 mcg/m L) in a 100 m L glass bottle. Anesthesia: Initial: 0.2 to 0.6 mg/kg IV over 30-60 seconds for induction of anesthesia; maintenance: 5-20 mcg/kg/minute.

Continuously monitor with pulse oximetry, electrocardiogram, and frequent blood pressure measurements.

Standard dosing regimen: initial intravenous bolus dose of 6.5 mg/kg followed by supplemental doses of 1.6 mg/kg as needed.

The dose for induction of anesthesia in adult patients and in pediatric patients above the age of ten (10) years will vary between 0.2 and 0.6 mg/kg of body weight, and it must be individualized in each case.

The usual dose for induction in these patients is 0.3 mg/kg, injected over a period of 30 to 60 seconds.

Patients with severe systemic disease (ASA P3 or P4) should receive the modified dosing regimen.

DOSAGE AND ADMINISTRATION: Use supplemental oxygen in all patients undergoing sedation with LUSEDRA.

Produces rapid induction of anesthesia with minimal cardiovascular effects.

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